Updated analysis of KRAS/NRAS and BRAF mutations in study 20050181 of panitumumab (pmab) plus FOLFIRI for second-line treatment (tx) of metastatic colorectal cancer (mCRC).

6533b854fe1ef96bd12ae823

RESEARCH PRODUCT

Updated analysis of KRAS/NRAS and BRAF mutations in study 20050181 of panitumumab (pmab) plus FOLFIRI for second-line treatment (tx) of metastatic colorectal cancer (mCRC).

A.s. Jung Marc Peeters Cornelis J. A. Punt Emily Chan Andrés Cervantes Eric Van Cutsem Andrew Strickland Florian Lordick Laslo Roman Michel Ducreux Scott D. Patterson Alberto Sobrero Hua Yu Yevhen Hotko Timothy J. Price Gregory C. Wilson Thierry André Tudor Ciuleanu Kelly S. Oliner Roger Sidhu

subject

Neuroblastoma RAS viral oncogene homolog Oncology Cancer Research medicine.medical_specialty Second line treatment business.industry Colorectal cancer Bioinformatics medicine.disease medicine.disease_cause Oncology Internal medicine FOLFIRI Medicine Panitumumab KRAS business neoplasms medicine.drug

description

3568 Background: Previously, extended RAS analysis from this study showed a trend toward improvements in HR on OS and PFS with pmab + FOLFIRI vs FOLFIRI in WT RAS group vs WT KRAS exon 2 group. Her...

year	journal	country	edition	language
2014-05-20	Journal of Clinical Oncology

https://doi.org/10.1200/jco.2014.32.15_suppl.3568

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