Changes in glutamatergic neurotransmission within the migraine cycle

6533b854fe1ef96bd12aeaa9

RESEARCH PRODUCT

Changes in glutamatergic neurotransmission within the migraine cycle

Filippo Brighina Piera Paladino Brigida Fierro Giuseppe Cosentino

subject

medicine.medical_specialty Neurology business.industry medicine.medical_treatment Clinical Neurology General Medicine Neurotransmission Neurophysiology medicine.disease Transcranial magnetic stimulation Glutamatergic Anesthesiology and Pain Medicine Migraine Poster Presentation medicine Neurology (clinical)business Neuroscience

description

Background Although some neurophysiological studies have showed cortical excitability changes during different phases of the migraine cycle, the pathophysiological mechanisms underlying attacks recurrence remain unknown. Here we evaluated the response of the migraine motor-cortex to brief trains of 5-Hz repetitive transcranial magnetic stimulation (rTMS) in order to study, indirectly, presynaptic mechanisms of glutamatergic neurotransmission across the different phases of the migraine cycle.

year	journal	country	edition	language
2013-02-01	The Journal of Headache and Pain

https://doi.org/10.1186/1129-2377-14-s1-p126

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