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RESEARCH PRODUCT
Organic synthesis of high added value molecules with MOF catalysts
Nuria MartínFrancisco G. Cirujanosubject
Chemistry OrganicBiochemistryCatalysischemistry.chemical_compoundLEVULINIC ACIDALLYLIC ALCOHOLSMoleculePhysical and Theoretical ChemistryConfined spaceScience & TechnologyChemistryOrganic ChemistryMesoporous silicaMISSING-LINKER DEFECTSTransition stateMESOPOROUS MATERIALSChemistryRECYCLABLE CATALYSTChemical engineeringHETEROGENEOUS CATALYSISC-CMETALPhysical SciencesACTIVE-SITESOrganic synthesisPorous solidsMesoporous materialPROSTAGLANDIN UNSATURATED-KETONESdescription
Recent examples of organic synthesis of fine chemicals and pharmaceuticals in confined spaces of MOFs are highlighted and compared with silica-based ordered porous solids, such as zeolites or mesoporous (organo)silica. These heterogeneous catalysts offer the possibility of stabilizing the desired transition states and/or intermediates during organic transformations of functional groups and (C-C/C-N) bond forming steps towards the desired functional high added value molecular scaffolds. A short introduction on zeolites, mesoporous silica and metal-organic frameworks is followed by relevant applications in which confined active sites in the pores promote single or multi-step organic synthesis of industrially relevant molecules. A critical discussion on the catalytic performances of the different types of hybrid inorganic-organic catalysts in the synthesis of O- and N-containing acyclic and heterocyclic molecules has been presented. ispartof: ORGANIC & BIOMOLECULAR CHEMISTRY vol:18 issue:40 pages:8058-8073 ispartof: location:England status: published
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-10-28 | Organic & Biomolecular Chemistry |