ChemInform Abstract: Polycondensed Nitrogen Heterocycles. Part 17. Isoxazolo(4,3-d)pyrazolo-(3,4-f)(1,2,3)triazepine. A New Ring System.

6533b854fe1ef96bd12af2cf

RESEARCH PRODUCT

ChemInform Abstract: Polycondensed Nitrogen Heterocycles. Part 17. Isoxazolo(4,3-d)pyrazolo-(3,4-f)(1,2,3)triazepine. A New Ring System.

Giuseppe Presti Girolamo Cirrincione Enrico Aiello Anna Maria Almerico Gaetano Dattolo

subject

chemistry.chemical_element General Medicine Clostridium perfringens Ring (chemistry)medicine.disease_cause Nitrogen Medicinal chemistry Coupling reaction Salmonella cholerasuis chemistry.chemical_compound chemistry Intramolecular force Nitration medicine

description

The title compounds were prepared by nitration of compounds 2, reduction of the dinitro derivatives 4 and diazotization of the diamino derivatives 6 followed by an intramolecular coupling reaction. Compound 4a showed good activity against Salmonella cholerasuis and Clostridium perfringens bacteria.

year	journal	country	edition	language
1988-04-12	ChemInform

https://doi.org/10.1002/chin.198815261

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