6533b854fe1ef96bd12af555
RESEARCH PRODUCT
Modifications induced on the amygdaloid paroxysmal activity by entopeduncolar or nigral injection of kainic acid, in the cat.
Benigno AV. RaieliGiuseppe Crescimannosubject
medicine.medical_specialtyKainic acidPyrrolidinesTime FactorsPhysiologyMonosodium glutamateBiologyBiochemistryTonic (physiology)chemistry.chemical_compoundEpilepsyInternal medicineBasal gangliamedicineCarnivoraAnimalschemistry.chemical_classificationDecerebrate StateKainic AcidFissipediabiology.organism_classificationmedicine.diseaseAmygdalaAmino acidElectrophysiologySubstantia NigraEndocrinologynervous systemchemistryCatsdescription
Entopeduncolar or nigral injection of kainic acid determines an early decrease of the evoked amygdaloid paroxysmal activity and a later increase of the after discharge duration. This biphasic effect is likely due to the structural analogy of the drug with monosodium glutamate, a neuroexcitant amino acid. The data suggest that the basal ganglia exert a tonic control on the amygdaloid activity.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1983-12-01 | Archives internationales de physiologie et de biochimie |