6533b854fe1ef96bd12af568

RESEARCH PRODUCT

Ultrastructural observations on the central innervation of the guinea-pig pineal gland.

P. SemmLutz VollrathT. Schneider

subject

Maleendocrine systemCytoplasmHistologyGuinea PigsBiologySynaptic vesicleNerve Fibers MyelinatedPineal GlandPathology and Forensic MedicineGuinea pigPineal glandNerve FibersEpendymamedicineNeuropilEpithalamusAnimalsCell NucleusCell BiologyAnatomyMicroscopy Electronmedicine.anatomical_structurenervous systemHypothalamusSynapsesUltrastructureSynaptic VesiclesEpendymahormones hormone substitutes and hormone antagonists

description

In the present study the central innervation of the guinea-pig pineal gland was investigated. The habenulae and the pineal stalk contain myelinated and non-myelinated nerve fibres with few dense-cored and electron-lucent vesicles. Some myelinated fibres leave the main nerve fibre bundles, lose their myelin-sheaths and terminate in the pineal gland. Although direct proof is lacking, the non-myelinated fibres appear to end near the site where the bulk of the myelinated fibres are located. Here a neuropil area exists where synapses between non-myelinated fibre elements are abundant. Neurosecretory fibres were also seen. The results support the concept of functional interrelationships between hypothalamus, epithalamus and the pineal gland.

yearjournalcountryeditionlanguage
1981-09-01Cell and tissue research
10.1007/bf00209964https://pubmed.ncbi.nlm.nih.gov/7273131