6533b855fe1ef96bd12afcfe

RESEARCH PRODUCT

Methodological Issues in the Baffling Relationship Between Hepatitis C Virus and Non Hodgkin’s Lymphomas

Daria MendolaStefano De CantisEmilio Iannitto

subject

Hodgkin sbusiness.industryHepatitis C virusMixed cryoglobulinemiaConfoundingmedicinemedicine.diseasemedicine.disease_causebusinessVirologyClinical psychologyLymphoma

description

The association between Hepatitis C Virus infection and B-cell Non-Hodgkin’s Lymphoma has been the matter of several studies: they showed disagreeing results with a marked regional variability. In this paper we present a review of the literature, highlighting methodological issues and main statistically critical aspects. Review suggests that studies were often not methodologically well approached. Moreover, we present main results from an original case-control study conducted in Italy, in an area of high endemicity of Hepatitis C Virus infection. In particular, we put attention in selection of a properly matching control group and in the role of age as a confounding variable.

yearjournalcountryeditionlanguage
2003-01-01
https://doi.org/10.1007/978-3-642-18991-3_74