6533b855fe1ef96bd12b0089

RESEARCH PRODUCT

Enteral Nutrition in Pancreaticoduodenectomy: A Literature Review

Gabriele SpinelliS. FicarellaGiulia Lo MonteAntonio MarrazzoVincenzo Davide PalumboGiuseppe DamianoAttilio Ignazio Lo MonteSalvatore Buscemi

subject

medicine.medical_specialtydelayed gastric emptyingGastroparesismedicine.medical_treatmentlcsh:TX341-641ReviewPancreaticoduodenectomylaw.inventionPancreatic FistulaEnteral NutritionPostoperative ComplicationsMeta-Analysis as TopicRandomized controlled trialRisk FactorslawmedicineHumansGastroparesisRandomized Controlled Trials as TopicNutrition and DieteticsGastric emptyingEnteral nutrition; pancreaticoduodenectomy; delayed gastric emptying; postoperative pancreatic fistula; postpancreatectomy hemorrhagebusiness.industryGeneral surgeryGold standardPerioperativeLength of Staymedicine.diseasePancreaticoduodenectomySurgerySettore MED/18 - Chirurgia GeneraleTreatment OutcomeParenteral nutritionPancreatic fistulapostoperative pancreatic fistulabusinesslcsh:Nutrition. Foods and food supplypostpancreatectomy hemorrhageFood Science

description

Pancreaticoduodenectomy (PD) is considered the gold standard treatment for periampullory carcinomas. This procedure presents 30%–40% of morbidity. Patients who have undergone pancreaticoduodenectomy often present perioperative malnutrition that is worse in the early postoperative days, affects the process of healing, the intestinal barrier function and the number of postoperative complications. Few studies focus on the relation between enteral nutrition (EN) and postoperative complications. Our aim was to perform a review, including only randomized controlled trial meta-analyses or well-designed studies, of evidence regarding the correlation between EN and main complications and outcomes after pancreaticoduodenectomy, as delayed gastric emptying (DGE), postoperative pancreatic fistula (POPF), postpancreatectomy hemorrhage (PPH), length of stay and infectious complications. Several studies, especially randomized controlled trial have shown that EN does not increase the rate of DGE. EN appeared safe and tolerated for patients after PD, even if it did not reveal any advantages in terms of POPF, PPH, length of stay and infectious complications.

yearjournalcountryeditionlanguage
2015-04-01Nutrients
https://doi.org/10.3390/nu7053154