P-76D-PENICILLAMINE, AN ACETALDEHYDE SEQUESTERING AGENT, REDUCES ETHANOL PREFERENCE IN ALCOHOL-NAÏVE RATS

6533b855fe1ef96bd12b06aa

RESEARCH PRODUCT

P-76D-PENICILLAMINE, AN ACETALDEHYDE SEQUESTERING AGENT, REDUCES ETHANOL PREFERENCE IN ALCOHOL-NAÏVE RATS

Lucía Martí-prats O. Peñuela M. J. Cano-cebrián Yolanda Campos-jurado Teodoro Zornoza Alejandro Orrico

subject

Ethanol preference chemistry.chemical_compound Ethanol Biochemistry Chemistry Penicillamine medicine Acetaldehyde Alcohol Sequestering Agent General Medicine Pharmacology medicine.drug

description

In previous investigations, we demonstrated that D-penicillamine (DP), a sulfhydryl aminoacid which has been studied as sequestration agent of acetaldehyde (ACD), is able to prevent the alcohol deprivation effect (ADE) but not voluntary ethanol consumption. Both results were obtained in long-term ethanol-experienced Wistar rats. Based on a previous …

year	journal	country	edition	language
2015-09-01	Alcohol and Alcoholism

https://doi.org/10.1093/alcalc/agv080.76

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