6533b855fe1ef96bd12b06ff

RESEARCH PRODUCT

Styryl-lactones from the stem bark of Goniothalamus arvensis

K. Sundar RaoAlmudena BermejoDiego CortesM. Amparo Blázquez

subject

Stem barkbiologyStereochemistryPlant ScienceGeneral MedicineFractionationbiology.organism_classificationMass spectrometryBiochemistryAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicinechemistryAnnonaceaeDrug DiscoveryMolecular MedicineDerivatizationGoniothalamusFood Science

description

The fractionation of the methanolic extract of Goniothalamus arvensis (Annonaceae) stem bark led to the isolation of two novel styryl-lactones, arvensin and (+)-2-epi-altholactone. The structures of these compounds, which belong to the furano-pyrone group, were established on the basis of mass spectrometry, one- and two-dimensional nuclear magnetic resonance experiments, as well as simple chemical derivatization. The relative and absolute configurations of the compounds are discussed. Copyright © 1999 John Wiley & Sons, Ltd.

https://doi.org/10.1002/(sici)1099-1565(199905/06)10:3<127::aid-pca451>3.0.co;2-5