6533b855fe1ef96bd12b09b0
RESEARCH PRODUCT
Auditory event-related potentials (P300) in epileptic patients.
G RaspantiG. CaravagliosE. NatalèOrnella DanieleGiuseppe FerraroBrigida Fierrosubject
AdultMalemedicine.medical_specialtyAdolescentAuditory eventAuditory oddballAudiologyCentral nervous system diseaseEpilepsyCognitionEvent-related potentialSeizuresPhysiology (medical)medicineHumansLatency (engineering)ChildAgedSeizure frequencyEpilepsyGeneral MedicineMiddle Agedmedicine.diseaseEvent-Related Potentials P300NeurologyEvoked Potentials AuditoryBrain lesionsRegression AnalysisAnticonvulsantsFemaleNeurology (clinical)Psychologydescription
Auditory event-related potentials (AERPs) were recorded during an auditory oddball paradigm in 108 epileptics and in 32 healthy controls. P300 latency varied in relationship with age only in controls. Symptomatic epileptics had significantly prolonged P300 mean latency compared to those without detectable brain lesion(s) on MR scan. Moreover, these latter patients were compared on the basis of epilepsy duration, type of seizure, seizure frequency and antiepileptic treatment; the application of a multiple regression model showed a significant relationship between P300 latency prolongation and epilepsy duration, seizure frequency and polytherapy.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-04-01 | Neurophysiologie clinique = Clinical neurophysiology |