6533b855fe1ef96bd12b09ba

RESEARCH PRODUCT

Embryotoxicity studies of tri-n-butyltin(IV) complexes of 5-[(E)-2-(aryl)-1-diazenyl]-2-hydroxybenzoic acid and 2-[(E)-2-(3-formyl-4-hydroxyphenyl)-1-diazenyl] benzoic acid on sea urchin development

Keisham Surjit SinghTushar S. Basu BaulLorenzo PelleritoPaolo D'agatiWandondor RynjahClaudia Pellerito

subject

chemistry.chemical_classificationSPECTRUMAzo compoundbiologyStereochemistryCarboxylic acidArylSMALL-SCALE ANISOTROPYGeneral ChemistryPhenolic acidbiology.organism_classificationParacentrotus lividusENERGY COSMIC-RAYSInorganic Chemistrychemistry.chemical_compoundchemistrybiology.animalSphaerechinus granularisSea urchinBenzoic acid

description

The toxicity studies of free 5-[(E)-2-(aryl)-1-diazenyll-2-hydroxybenzoic acid and 2-[(E)-2-(3-formyl-4-hydroxyphenyl)-1-diazenyllbenzoic acid and their tri-n-butyltin(IV) complexes were evaluated by using sea urchin early developmental stages as recommended model organisms for toxicity tests. The novel complexes, as the parent tri-n-butyltin(IV) chloride (TBTCl), caused mitosis block and induced high embryonic mortality in sea urchin. Copyright (c) 2005 John Wiley & Sons, Ltd.

https://doi.org/10.1002/aoc.971