6533b855fe1ef96bd12b0a8b

RESEARCH PRODUCT

Recent advances in the synthesis of functionalised monofluorinated compounds.

Daniel M. SedgwickSantos FusteroPablo BarrioRaquel Román

subject

Allylic rearrangement010405 organic chemistryChemistryMetals and AlloysEnantioselective synthesisGeneral Chemistry010402 general chemistry01 natural sciencesCombinatorial chemistryCatalysis0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsOrganic moleculesCatalysisNucleophileOrganocatalysisElectrophileMaterials ChemistryCeramics and Composites

description

Over the past few years, we have tackled the synthesis of interesting monofluorinated organic molecules, such as: dihydronaphthalene derivatives, β-fluoro sulfones and related carbonyl compounds, fluorohydrins and allylic alcohols. Overall, a wide range of modern synthetic techniques are covered in this feature article including transition-metal, photo- and organocatalysis, nucleophilic and electrophilic fluorinations, chiral auxiliaries and enantioselective catalysis.

10.1039/c8cc05181jhttps://pubmed.ncbi.nlm.nih.gov/30066002