6533b855fe1ef96bd12b1377

RESEARCH PRODUCT

Influence of operative strategy for the aortic arch in DeBakey type I aortic dissection: Analysis of the German Registry for Acute Aortic Dissection Type A

Ernst WeigangJerry EasoMichael HorstPhilipp P.f. HölzlMaria BlettnerIsabell HoffmannOtto Dapunt

subject

MaleAortic archPulmonary and Respiratory Medicinemedicine.medical_specialtyTime FactorsElephant trunksRisk AssessmentGroup Blaw.inventionBlood Vessel Prosthesis ImplantationPostoperative ComplicationsAneurysmRisk FactorslawGermanymedicine.arteryInternal medicineAscending aortamedicineHumansRegistriesAgedAortic dissectionbusiness.industryPerioperativeMiddle Agedmedicine.diseaseIntensive care unitAortic AneurysmSurgeryAortic DissectionLogistic ModelsTreatment OutcomeAcute DiseaseCardiologyFemaleSurgerybusinessCardiology and Cardiovascular Medicine

description

Objective Patients treated with an extensive approach including total aortic arch replacement for acute aortic dissection type A may have a favorable long-term prognosis by treating the residual false lumen. Our goal was to analyze the operative strategy for treatment of type I DeBakey aortic dissection from the German Registry for Acute Aortic Dissection Type A (GERAADA) data. Methods A total of 658 patients with type I DeBakey aortic dissection and entry only in the ascending aorta were identified in the GERAADA. Patients in group A underwent replacement of the ascending aorta with hemiarch replacement. Patients in group B received extensive treatment with total arch replacement or conventional or frozen elephant trunk. Results A total of 518 patients in group A and 140 patients in group B were treated. There was an overall 30-day mortality of 20.2% (n = 133). Group A had a slightly lower rate of mortality with 18.7% (n = 97) compared with 25.7% for group B (n = 36), but with no statistical significant difference ( P  = .067). The onset of new neurologic deficit (13.6% in group vs 12.5% in group B, P  = .78) and new malperfusion deficit (8.4% in group A vs 10.7% in group B, P  = .53) showed no statistical difference. Conclusions On analysis of the GERAADA data, it seems that a more aggressive approach of aortic arch treatment can be applied without higher perioperative risk even in the onset of acute aortic dissection type A. Long-term follow-up data analysis will be necessary to offer the optimal surgical strategy for different patient groups.

10.1016/j.jtcvs.2011.07.066http://dx.doi.org/10.1016/j.jtcvs.2011.07.066