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RESEARCH PRODUCT
Design of guanidinium porphyrins as potential G-quadruplex ligands
Claude P. GrosHai-jun XuPhilippe RichardJean-michel Barbesubject
chemistry.chemical_compoundchemistryStereochemistryLigandPhthalocyanineMoleculeGeneral ChemistryG-quadruplexPorphyrinGuanidine derivativesdescription
We report herein an easy and smooth synthesis of two novel tetra-meso-substituted porphyrins bearing terminal guanidinium functionalities. These two guanidine derivatives are the porphyrin-based analogs of ZnPC , a closely related phthalocyanine-based molecule with four guanidinium arms already reported as an efficient G-quadruplex ligand.
year | journal | country | edition | language |
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2012-10-01 | Journal of Porphyrins and Phthalocyanines |