6533b856fe1ef96bd12b3049
RESEARCH PRODUCT
Triggers of Exacerbation in Chronic Urticaria and Recurrent Angioedema—Prevalence and Relevance
Anete Sevciovic GrumachWilliam R. LumryRicardo Cardona VillaPetra Staubach-renzImke ReeseSusana Diez-zuluagasubject
Chronic conditionmedicine.medical_specialtyUrticariaExacerbationDiseaseImmunoglobulin EC1-inhibitor03 medical and health sciences0302 clinical medicineimmune system diseasesPrevalencemedicineHumansImmunology and AllergyChronic Urticaria030212 general & internal medicineAngioedemaskin and connective tissue diseasesIntensive care medicineChronic urticariabiologyAngioedemabusiness.industrymedicine.disease030228 respiratory systemChronic DiseaseHereditary angioedemabiology.proteinmedicine.symptombusinessdescription
Patients with urticaria and angioedema often have triggers that cause an outbreak or a swelling episode or worsen their chronic condition. Exploring these factors with each patient may result in better understanding and control of their disease. Patients should be advised to avoid known triggers, if feasible, or prepare to prevent or control an exacerbation with appropriate pretreatment if avoidance is not possible. In this review, we describe and discuss a variety of factors for which there is evidence that they cause or exacerbate chronic spontaneous urticaria and angioedema. These potentially exacerbating factors include drugs, food additives, and naturally occurring pseudoallergens, mental stress, and trauma.
year | journal | country | edition | language |
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2021-03-10 | The Journal of Allergy and Clinical Immunology: In Practice |