6533b857fe1ef96bd12b39c4

RESEARCH PRODUCT

Barbiturate jaundice

Franco AgugliaLuigi PagliaroG. Campesi

subject

medicine.medical_specialtyHepatologybiologyExacerbationmedicine.diagnostic_testbusiness.industrymedicine.drug_classGastroenterologyJaundiceBarbitalGastroenterologyAlanine transaminaseBarbiturateAnesthesiaInternal medicinebiology.proteinMedicineIngestionPhenobarbitalmedicine.symptombusinessLiver function testsmedicine.drug

description

Summary A case of barbital-induced jaundice is described. The patient, a 31-year-old woman, developed generalized skin eruption, mucosal lesions, and fever 2 hr after the ingestion of 2 tablets of a barbital-containing drug (Veramon). She then developed a deep cholestatic jaundice which lasted more than 7 months. During the remission of jaundice, a rechallenge with phenobarbital caused a recurrence of fever and skin eruption, with exacerbation of jaundice.

yearjournalcountryeditionlanguage
1969-05-01Gastroenterology
https://doi.org/10.1016/s0016-5085(69)80099-5