6533b857fe1ef96bd12b39dd

RESEARCH PRODUCT

Triterpenoid Saponins From the Stem Bark of Pentaclethra eetveldeana

Tomofumi MiyamotoClément DelaudeMarie Aleth Lacaille-duboisMpuza KapunduChiaki TanakaDavid PertuitAnne Claire Mitaine-offer

subject

PharmacologyStem barkTraditional medicine010405 organic chemistryPlant ScienceGeneral MedicineFabaceaeBiology01 natural sciencesPentaclethra eetveldeana0104 chemical sciences010404 medicinal & biomolecular chemistryTriterpenoidComplementary and alternative medicineDrug Discovery

description

Two previously undescribed triterpenoid saponins together with 4 known ones were isolated from the stem bark of Pentaclethra eetveldeana De Wild. & Th. Dur. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR experiments in combination with mass spectrometry as 3- O-β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyloleanolic acid and 3- O-β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosylhederagenin.

https://doi.org/10.1177/1934578x19863947