6533b857fe1ef96bd12b43dd

RESEARCH PRODUCT

Determination of chromophore distribution in skin by spectral imaging

Inga SakniteDainis JakovelsJānis SpigulisMarta Lange

subject

medicine.medical_specialtyMaterials sciencebusiness.industryPhotodetectorChromophorelaw.inventionSpectral imagingImaging spectroscopyOpticslawmedicineOptoelectronicsRGB color modelDiffuse reflectionbusinessAbsorption (electromagnetic radiation)Light-emitting diode

description

Possibilities to determine chromophore distribution in skin by spectral imaging were explored. Simple RGB sensor devices were used for image acquisition. Totally 200 images of 40 different bruises of 20 people were obtained in order to map chromophores bilirubin and haemoglobin. Possibilities to detect water in vitro and in vivo were estimated by using silicon photodetectors and narrow band LEDs. The results show that it is possible to obtain bilirubin and haemoglobin distribution maps and observe changes of chromophore parameter values over time by using a simple RGB imaging device. Water in vitro was detected by using differences in absorption at 450 nm and 950 nm, and 650 nm and 950 nm.

https://doi.org/10.1117/12.930952