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RESEARCH PRODUCT
Frequency and Characterization of Benign Lesions in Patients Undergoing Surgery for the Suspicion of Solid Pancreatic Neoplasm
Anisha KumarPeter MildenbergerLuca FrulloniRalf KiesslichAntonio AmodioLuigi BeniniFrancesco VitaliItalo VantiniTorsten HansenStefan Heinrichsubject
AdultMalemedicine.medical_specialtyAdolescentEndocrinology Diabetes and Metabolismmedicine.medical_treatmenteducationSymptom assessmentChoristomaUnnecessary ProceduresAutoimmune DiseasesDiagnosis DifferentialYoung AdultPancreatectomyEndocrinologyGermanyhemic and lymphatic diseasesDiagnosis80 and overPrevalenceInternal MedicineHumansMedicineNeoplasmIn patientAgedRetrospective StudiesAged 80 and overAdolescent; Adult; Aged; Aged 80 and over; Autoimmune Diseases; Choristoma; Diagnosis Differential; Female; Germany; Humans; Male; Middle Aged; Pancreatectomy; Pancreatic Diseases; Pancreatic Neoplasms; Pancreatitis; Prevalence; Retrospective Studies; Spleen; Symptom Assessment; Unnecessary Procedures; Young AdultHepatologybusiness.industryGastroenterologyPancreatic DiseasesCancerRetrospective cohort studyMiddle Agedmedicine.diseaseSurgeryPancreatic NeoplasmsPancreatitisDifferentialPancreatectomyPancreatitisFemaleRadiologySymptom AssessmentDifferential diagnosisbusinessSpleendescription
A diagnosis of benign lesions (BLs) is reported in 5% to 21% of pancreatoduodenectomies performed for neoplasms; no data for body-tail resections are available. The aims were to investigate the frequency and characterize the BLs mimicking cancer in the head and the body-tail of the pancreas.This study is a retrospective review of pancreatic specimenscollected from 2005 to 2011 in the pathology database of Mainz (Germany). Patients with final diagnosis excluding malignancy were analyzed by histology, imaging, and clinical aspects.Among 373 patients, 33 patients (8.8%) were diagnosed with a benign disease: 25 (8.4%) of 298 in the pancreatic head and 8 (10.7%) of 75 in the body-tail resections. Paraduodenal pancreatitis was diagnosed in 13 (3.5%) of 373 patients; autoimmune pancreatitis (AIP), in 11 (2.9%); "ordinary" chronic pancreatitis, in 6 (1.6%); and accessory spleen, in 3 (0.8%). In pancreatic head resections, the most frequent diagnoses were paraduodenal pancreatitis (13/298, 4.4%) and AIP (9/298, 3%), whereas in the body-tail, the most frequent diagnoses were accessory spleen (3/75, 4%), chronic pancreatitis (3/75, 4%), and AIP (2/75, 2.7%).Benign lesions are observed with the same frequency inspecimens of the head or the body-tail of the pancreas.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-05-01 | Pancreas |