6533b857fe1ef96bd12b4c95
RESEARCH PRODUCT
Auswirkungen der Sauerstoffinhalation auf die Hämodynamik bei chronischer thromboembolischer pulmonaler Hypertonie
Christoph DüberMichael B. PittonManfred ThelenE. Mayersubject
Inhalationbusiness.industryRespiratory diseaseCardiac indexmacromolecular substancesmedicine.diseasePulmonary hypertensionmedicine.anatomical_structureBlood pressureAnesthesiamedicine.arteryPulmonary arteryVascular resistancemedicineRadiology Nuclear Medicine and imagingbusinessOxygen saturation (medicine)description
PURPOSE This study evaluates the haemodynamic effects of oxygen inhalation on pulmonary artery pressure and pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension. METHOD In 47 patients with chronic thromboembolic pulmonary hypertension haemodynamic parameters were measured before and after oxygen inhalation. RESULTS In moderately severe and severe pulmonary hypertension oxygen inhalation significantly reduced mean pulmonary artery pressure by about 11.1% and 4.6%, respectively. However, pulmonary vascular resistance was not significantly affected. Oxygen saturation improved and heart rate was reduced. Cardiac index decreased in severe pulmonary hypertension. Systemic vascular resistance increased. CONCLUSION We conclude that oxygen inhalation reduces pulmonary artery pressure and improves oxygen supply in patients with moderately severe and severe chronic thromboembolic pulmonary hypertension.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1998-01-01 | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren |