6533b857fe1ef96bd12b4ca2
RESEARCH PRODUCT
Catalytic aminomercuration of olefins in a tandem aminomercuration-deoxymercuration; One-step synthesis of secondary n-arylallylamines from allylalcohols
Julia Pérez-prietoJosé BarluengaGregorio Asensiosubject
Reaction mechanismTetrafluoroborateOrganic ChemistryBiochemistryCatalysisAdductchemistry.chemical_compoundAnilinechemistryDrug DiscoveryOrganic chemistryAmine gas treatingAliphatic compoundAminationdescription
Abstract Allyl alcohols react with primary aromatic amines and stoichiometric amounts of mercury(II) tetrafluoroborate to give mixtures of mono- and diallyl anilines. However, the use of the tandem aminomercuration-deoxymercuration promoted by catalytic mercury(II) tetrafluoroborate allows to perform regiospecifically the monoallylation reaction with very high yields. A mechanism is proposed to account for the observed results.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-01-01 | Tetrahedron |