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RESEARCH PRODUCT

Solid state structural studies of five bile acid derivatives

Jari TamminenManu LahtinenArto ValkonenErkki Kolehmainen

subject

Bile acidmedicine.drug_classChemistryOrganic ChemistryNuclear magnetic resonance crystallographyAnalytical ChemistryInorganic ChemistryCrystallinityCrystallographyPolymorphism (materials science)X-ray crystallographymedicineFourier transform infrared spectroscopyThermal analysisSingle crystalSpectroscopy

description

Five synthetically important bile acid derivatives have been characterized by 13 C CP-MAS, X-ray diffraction (both single crystal and powder), FTIR, and thermoanalytical (DSC and TG) methods. The crystallinity of all these derivatives is high, which can be deducted from the 13 C CP-MAS and powder X-ray diffraction data. Two of the compounds showed polymorphism, and one polymorph was structurally elucidated for both by comparing single crystal and powder X-ray diffraction data.

yearjournalcountryeditionlanguage
2008-08-01Journal of Molecular Structure
https://doi.org/10.1016/j.molstruc.2007.11.018