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RESEARCH PRODUCT

Blood Flow and Oxygenation Status of Head and Neck Carcinomas

Peter Vaupel

subject

Clinical OncologyOncologymedicine.medical_specialtyTumor hypoxiabusiness.industryOxygenationBlood flowHypoxia (medical)Tumor OxygenationInternal medicinemedicineClinical significancemedicine.symptombusinessHead and neck

description

Solid tumors contain a significant fraction of microregions which are chronically or transiently hypoxic. Experimental evidence is growing, showing that hypoxia may have a profound impact on malignant progression and on responsiveness to therapy [1–4].The clinical relevance of tumor oxygenation in human solid malignancies is under investigation (for a recent review see [5]). In this presentation, relevant clinical findings available to date on blood and oxygen supply of human head and neck carcinomas will be reviewed and emphasis will be given to the relevance of these factors in clinical oncology.

yearjournalcountryeditionlanguage
1997-01-01
https://doi.org/10.1007/978-1-4615-5399-1_13