6533b858fe1ef96bd12b582e

RESEARCH PRODUCT

Identification of Protein Complexes Associated with the Usher Syndrome 2C and Epilepsy-Associated Protein VLGR1 Applying Affinity Proteomics

Karsten BoldtNicola HornUwe WolfrumMarius UeffingBarbara KnappDeva Krupakar Kusuluri

subject

0301 basic medicineChemistryUsher syndromeGenomics02 engineering and technologyComputational biology021001 nanoscience & nanotechnologymedicine.diseaseProteomics03 medical and health sciencesEpilepsy030104 developmental biologymedicineIdentification (biology)Signal transduction0210 nano-technologyProtein networkCellular compartment

description

Authors aimed to identify novel VLGR1-associated protein networks to shed light on its integration into signaling pathways and the cellular compartments in which VLGR1 functions using high-resolution affinity proteomics based on tandem affinity purifications (TAPs).

https://doi.org/10.18547/gcb.2018.vol4.iss1.e100051