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RESEARCH PRODUCT
Synthesis of highly functionalized 9,10-phenanthrenequinones by oxidative coupling using MoCl5.
Siegfried R. WaldvogelSimon Trosiensubject
Models MolecularMolybdenumNatural productMolecular StructureOxidative CouplingOrganic ChemistryBond formationMolybdenum pentachloridePhenanthrenesPhotochemistryBiochemistryCombinatorial chemistrychemistry.chemical_compoundchemistryChloridesMoleculeOxidative coupling of methaneBenzilPhysical and Theoretical Chemistrydescription
The strong oxidative power of molybdenum pentachloride gives rise to an efficient oxidative C-C bond formation of benzil derivatives to the corresponding 9,10-phenanthrenequinones. A highly complementary method to previous approaches was developed. The required derivatives are accessible in a modular fashion and in excellent yields. By this approach the orchid-derived natural product cypripediquinone A was synthesized for the first time.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-06-05 | Organic letters |