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RESEARCH PRODUCT
Ancestral Reconstruction and Investigations of Genomic Recombination on some Pentapetalae Chloroplasts
Michel SalomonBassam AlkindyJean-françois CouchotBashar Al-nuaimiBashar Al-nuaimiChristophe Guyeuxsubject
Ancestral reconstructionMost recent common ancestor0206 medical engineeringGenomic recombination02 engineering and technology[INFO.INFO-SE]Computer Science [cs]/Software Engineering [cs.SE]Dynamic programmingGenome[INFO.INFO-IU]Computer Science [cs]/Ubiquitous ComputingEvolution Molecular[INFO.INFO-CR]Computer Science [cs]/Cryptography and Security [cs.CR]AsteralesGene duplication0202 electrical engineering electronic engineering information engineeringPattern matchingGenome ChloroplastRosaceaeResearch ArticlesPhylogenySequence (medicine)Recombination GeneticbiologyGeneral Medicinebiology.organism_classification[INFO.INFO-MO]Computer Science [cs]/Modeling and SimulationAncestral genome reconstructionApialesEvolutionary biology[INFO.INFO-MA]Computer Science [cs]/Multiagent Systems [cs.MA]020201 artificial intelligence & image processing[INFO.INFO-ET]Computer Science [cs]/Emerging Technologies [cs.ET][INFO.INFO-DC]Computer Science [cs]/Distributed Parallel and Cluster Computing [cs.DC]Pentapetalae chloroplasts020602 bioinformaticsTP248.13-248.65Biotechnologydescription
Abstract In this article, we propose a semi-automated method to rebuild genome ancestors of chloroplasts by taking into account gene duplication. Two methods have been used in order to achieve this work: a naked eye investigation using homemade scripts, whose results are considered as a basis of knowledge, and a dynamic programming based approach similar to Needleman-Wunsch. The latter fundamentally uses the Gestalt pattern matching method of sequence matcher to evaluate the occurrences probability of each gene in the last common ancestor of two given genomes. The two approaches have been applied on chloroplastic genomes from Apiales, Asterales, and Fabids orders, the latter belonging to Pentapetalae group. We found that Apiales species do not undergo indels, while they occur in the Asterales and Fabids orders. A series of experiments was then carried out to extensively verify our findings by comparing the obtained ancestral reconstruction results with the latest released approach called MLGO (Maximum Likelihood for Gene-Order analysis).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-12-01 | Journal of Integrative Bioinformatics |