6533b858fe1ef96bd12b629d

RESEARCH PRODUCT

Polystyrene-supported proline as recyclable catalyst in the Baylis–Hillman reaction of arylaldehydes and methyl or ethyl vinyl ketone

Francesca D'annaFrancesco GiacaloneMichelangelo GruttadauriaAdriana Mossuto MarculescuRenato Noto

subject

chemistry.chemical_classificationKetoneProcess Chemistry and TechnologySettore CHIM/06 - Chimica OrganicaGeneral ChemistryHeterogeneous catalysisorganocatalysis heterogeneous catalysis Baylis-Hilmann reactionCatalysisCatalysischemistry.chemical_compoundchemistryOrganocatalysisImidazoleOrganic chemistryBaylis–Hillman reactionPolystyreneProline

description

Abstract Polystyrene-supported proline has been used as co-organocatalyst (10 mol%) with imidazole (10 mol%) in the Baylis–Hillman reaction between methyl or ethyl vinyl ketone and arylaldehydes. Recycling studies showed that the proline resin can be used up to five cycles with high isolated yields. This study represents the first example of supported proline as heterogeneous catalyst in the above reaction and broaden the scope of this catalytic material.

yearjournalcountryeditionlanguage
2008-03-01Catalysis Communications
https://doi.org/10.1016/j.catcom.2007.12.015