6533b858fe1ef96bd12b64a9

RESEARCH PRODUCT

Description of a Simple, Specific, and Sensitive Test for the Detection of Detergent-Solubilized C3b Receptor

H. H. MusselT. EhlenManfred P. Dierich

subject

chemistry.chemical_classificationErythrocytesRosette FormationChemistryLymphoblastImmunologychemical and pharmacologic phenomenaHematologyBurkitt LymphomaMolecular biologyCell LineReceptors ComplementMembraneBiochemistryRosette formationSolubilizationHumansImmunology and AllergyReceptorGlycoproteinGlycoproteins

description

Abstract The C3b receptor was isolated from detergent-solubilized human erythrocyte membranes by a previously described technique (1). The receptor glycoprotein was shown to enhance EAC14oxy23b rosette formation with Raji lymphoblastoid cells. This provided a specific and sensitive test to detect the solubilized C3b receptor either in crude or highly purified form. The property of the C3b receptor tested by this assay appears to be analogous to properties of β1H.

yearjournalcountryeditionlanguage
1981-11-01Immunobiology
https://doi.org/10.1016/s0171-2985(81)80051-4