Identification of potential inhibitors targeting BRAF-V600E mutant melanoma cells.

6533b858fe1ef96bd12b64ef

RESEARCH PRODUCT

Identification of potential inhibitors targeting BRAF-V600E mutant melanoma cells.

Onat Kadioglu Mohamed E.m. Saeed Henry Johannes Greten Wynand P. Roos David Schrama Katharina Mayr Thomas A. Efferth

subject

Models Molecular Proto-Oncogene Proteins B-raf Protein Conformation Mutant Mutation Missense Dermatology Inhibitory Concentration 50 Structure-Activity Relationship Cell Line Tumor medicine Humans Point Mutation Molecular Targeted Therapy Precision Medicine Melanoma Protein Kinase Inhibitors Dose-Response Relationship Drug business.industry Melanoma Drug Repositioning medicine.disease Neoplasm Proteins BRAF V600E Molecular Docking Simulation Amino Acid Substitution Drug Design Cancer research Identification (biology)Drug Screening Assays Antitumor business

year	journal	country	edition	language
2020-05-26	Journal of the American Academy of Dermatology

10.1016/j.jaad.2020.07.069 https://pubmed.ncbi.nlm.nih.gov/32707252

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