6533b858fe1ef96bd12b654e

RESEARCH PRODUCT

Human papillomavirus infection in couples undergoing in vitro fertilization procedures: impact on reproductive outcomes.

Giovanni RuvoloRosaria SchillaciFrancesco FiorentinoLucia GiovannelliEleonora CefaluPiero AmmatunaPietro AlimondiAntonio Perino

subject

InfertilityAdultMalemedicine.medical_specialtyHuman papillomavirusmedicine.medical_treatmentReproductive technologyFertilization in VitroAbortionAlphapapillomavirusPregnancymedicineHumansProspective cohort studyGynecologyPregnancyFamily CharacteristicsIn vitro fertilisationbusiness.industryObstetricsPapillomavirus InfectionsHPV infectionPregnancy Outcomevirus diseasesObstetrics and Gynecologymedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaInfectious Disease Transmission VerticalClinical trialTreatment OutcomeReproductive MedicineInfertilityFemalebusiness

description

A prospective study was performed to assess the relationship between human papillomavirus (HPV) infection in 199 infertile couples and outcome of assisted reproductive technologies (ARTs). A highly statistically significant correlation between pregnancy loss rate (proportion of pregnancies detected by β-hCG that did not progress beyond 20 weeks) and positive HPV DNA testing in the male partner of infertile couples, compared with HPV negatives, was observed (66.7% vs. 15%).

yearjournalcountryeditionlanguage
2011-04-01Fertility and sterility
10.1016/j.fertnstert.2010.11.047https://pubmed.ncbi.nlm.nih.gov/21167483