6533b858fe1ef96bd12b6cc1

RESEARCH PRODUCT

Synthetic derivatives of aromatic abietane diterpenoids and their biological activities

Miguel A. Gonzalez

subject

PharmacologyMolecular StructureSynthetic derivativesOrganic ChemistryCarnosic acidGeneral MedicineTerpenoidFerruginolchemistry.chemical_compoundchemistryDrug DiscoveryOrganic chemistryDehydroabietic acidDiterpenesAbietane

description

Naturally occurring aromatic abietane diterpenoids (dehydroabietanes) exhibit a wide range of biological activities. A number of synthetic studies aimed at modifying the abietane skeleton in order to obtain new potential chemotherapeutic agents have been reported. In this study, the biological activities of synthetic derivatives of aromatic abietane diterpenoids are reviewed.

https://doi.org/10.1016/j.ejmech.2014.10.023