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RESEARCH PRODUCT
Health and Disease Imprinted in the Time Variability of the Human Microbiome
Jose Manuel MartíDaniel Martíínez-martííínezTeresa RubioCíííésar GraciaManuel PeíííéñaAmparo LatorreAndríííéñés MoyaCarlos P. GarayJack A. Gilbertsubject
0301 basic medicineScaling lawPhysiologySystems biologyPopulationlcsh:QR1-502microbiomeDiseaseGut floraBiochemistryMicrobiologylcsh:MicrobiologyHost-Microbe Biology03 medical and health sciences0302 clinical medicineGeneticsMicrobiomeeducationMolecular BiologyEcology Evolution Behavior and Systematicseducation.field_of_studymetagenomicsbiologyHuman microbiomesystems biologystabilitybiology.organism_classificationEditor's PickQR1-502Computer Science Applications030104 developmental biologyEvolutionary biologyMetagenomicsModeling and Simulationecological modeling030217 neurology & neurosurgeryResearch Articledescription
The human microbiota correlates closely with the health status of its host. This article analyzes the microbial composition of several subjects under different conditions over time spans that ranged from days to months. Using the Langevin equation as the basis of our mathematical framework to evaluate microbial temporal stability, we proved that stable microbiotas can be distinguished from unstable microbiotas. This initial step will help us to determine how temporal microbiota stability is related to a subject’s health status and to develop a more comprehensive framework that will provide greater insight into this complex system.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-03-01 | mSystems |