Oppenauer Oxidation of Secondary Alcohols with 1,1,1-Trifluoroacetone as Hydride Acceptor

6533b858fe1ef96bd12b6cfa

RESEARCH PRODUCT

Oppenauer Oxidation of Secondary Alcohols with 1,1,1-Trifluoroacetone as Hydride Acceptor

Jaime Martínez-ferrer Gregorio Asensio María Elena González Núñez Rossella Mello

subject

Primary (chemistry)Chemistry Hydride Alcohol oxidation Organic Chemistry Organic chemistry Oppenauer oxidation Primary alcohol Selectivity Acceptor

description

1,1,1-Trifluoroacetone (2a) reacts as a hydride-acceptor in the Oppenauer oxidation of secondary alcohols (1) in the presence of diethylethoxyaluminum. The oxidant allows for selective oxidation of secondary alcohols in the presence of primary alcohols.

year	journal	country	edition	language
2007-11-03	The Journal of Organic Chemistry

https://doi.org/10.1021/jo7016422

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