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RESEARCH PRODUCT

Israeli Spotted Fever in Sicily. Description of two cases and minireview

Anna GiammancoClaudia ColombaMarcello TrizzinoAntonio CascioManlio TolomeoDanilo Di BonaCelestino Bonura

subject

AdultMaleMicrobiology (medical)Settore MED/17 - Malattie InfettiveIsraeli spotted fever; Mediterranean spotted fever; Rickettsia israelensis; Microbiology (medical); Infectious DiseasesRhipicephalus sanguineus030231 tropical medicineBoutonneuse Feverlcsh:Infectious and parasitic diseases03 medical and health sciences0302 clinical medicinemedicineInternational literatureAnimalsHumanslcsh:RC109-216Rickettsia israelensi030212 general & internal medicineIsraelSicilyNormal rangebiologyMediterranean spotted feverGeneral Medicinebiology.organism_classificationmedicine.diseaseIsraeli spotted feverVirologySpotted feverBoutonneuse feverRickettsia conoriiInfectious DiseasesRickettsiaRickettsia israelensisVector (epidemiology)FemaleRickettsia conorii

description

Mediterranean spotted fever (MSF) is endemic in Italy, where Rickettsia conorii subsp. conorii was thought to be the only pathogenic rickettsia and Rhipicephalus sanguineus the vector and main reservoir. R. conorii subsp. israelensis, which belongs to the R. conorii complex, is the agent of Israeli spotted fever (ISF); apart from Israel, it has also been found in Italy (Sicily and Sardinia) and in different regions of Portugal. We describe here two severe cases of ISF which occurred in otherwise healthy Italian adults. Their characteristics are analyzed and discussed in the light of other 91 cases found through a systematic review of international literature.

https://doi.org/10.1016/j.ijid.2017.04.003