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RESEARCH PRODUCT
α,ω-Functionalized poly-N-isopropylacrylamides: controlling the surface activity for vesicle adsorption by temperature
Patrick TheatoRudolf Zentelsubject
chemistry.chemical_classificationComonomerVesiclePolymerLower critical solution temperatureSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsBiomaterialschemistry.chemical_compoundColloid and Surface ChemistryAdsorptionMonomerchemistryChemical engineeringAcrylamidePolymer chemistryCopolymerdescription
The synthesis of alpha,omega-end-functionalized copolymers of N-isopropylacrylamide and N-(3-dimethylaminopropyl)acrylamide was performed. Monomer ratios of 100:0, 96:4, and 81:19 were investigated. The lower critical solution temperature (LCST) of these polymers was determined by cloud-point measurements and by microcalorimetric measurements. The LCST increased from 32 over 37 to 47 degrees C as the hydrophobicity increased with increasing amount of comonomer N-(3-dimethylaminopropyl)acrylamide. The polymers could successfully be adsorbed onto gold surfaces. Finally, vesicle adsorption onto these self-assembled polymer films on flat gold surfaces was investigated as the vesicle solution temperature was varied. It could be observed that vesicle adsorption was hindered as long as the temperature of the vesicle solution was above the LCST of the polymer. As soon as it dropped below the LCST the vesicle adsorption process was initiated.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-11-13 | Journal of Colloid and Interface Science |