6533b859fe1ef96bd12b75a7

RESEARCH PRODUCT

The Development of Novel Approaches to the Identification of Chemical and Protein Respiratory Allergens

Stefan UhligSusan GibbsDavid B. WarheitCostanza RovidaJean F. RegalYuksel CetinSilvia CasatiErwin Ludo RoggenRebecca J. DearmanIan KimberMichaela AufderheideIris Hermanns

subject

Alternative methodsMedical Laboratory Technologymedicine.medical_specialtyScope (project management)business.industryRespiratory HypersensitivityMedicineIdentification (biology)General MedicineToxicologybusinessIntensive care medicineGeneral Biochemistry Genetics and Molecular Biology

description

In October 2006, the European Centre for theValidation of Alternative Methods (ECVAM) spon-sored and hosted a three-day workshop to consideropportunities and challenges in the development ofalternative methods for the identification and char-acterisation of chemical respiratory allergens. Theproceedings, conclusions and recommendations ofthat workshop were subsequently made available asECVAM Workshop Report 60 (1).In April 2008, a second meeting was convenedby ECVAM to consider what progress has beenmade in the light of the recommendations derivedfrom the 2006 Workshop and the publishedreport. This meeting had as a second objective —to consider whether new opportunities for theidentification and characterisation of chemicalrespiratory allergens had emerged since 2006. Inaddition, the scope of the meeting was broadenedto also include an examination of new and emerg-ing approaches that may be appropriate for theevaluation of the respiratory sensitising potentialof proteins.

https://doi.org/10.1177/026119290803600514