6533b859fe1ef96bd12b7f50
RESEARCH PRODUCT
Untersuchungen zurFriesschen Verschiebung von Estern derortho- undpara-Methoxybenzoes�ure
Nicole GrosRobert MartinHermann KämmererVolker Böhmersubject
Solventchemistry.chemical_compoundNitromethaneFries rearrangementChemistryOrganic chemistryGeneral ChemistryBenzoatesDemethylationdescription
TheFries rearrangement of different methoxy benzoates has been investigated. Frompara-methoxy benzoates the corresponding hydroxy-4′-methoxy benzophenones could be obtained in good yields by treatment withLewis acids (especially TiCl4) in nitromethane at 20°C (4-hydroxy derivatives) or without solvent at 120°C (2-hydroxy derivatives). Under the same conditions only demethylation occurs withortho-methoxy benzoates leading to the corresponding salicylates. Small amounts of hydroxy-2′-methoxy benzophenones were obtained by treatment with polyphosphoric acid.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1979-01-01 | Monatshefte f�r Chemie |