6533b859fe1ef96bd12b8033

RESEARCH PRODUCT

Intratumoral PO2 Histography as Predictive Assay in Advanced Cancer of the Uterine Cervix

Birgit VorndranPaul Georg KnapsteinPeter VaupelMichael HöckelClaudia KnoopKarlheinz Schlenger

subject

Oncologymedicine.medical_specialtyUterine cervixTumor hypoxiabusiness.industryInternal medicinemedicineIn patientTumor OxygenationSolid tumorbusinessAdvanced cancerNonsurgical treatment

description

Experimental evidence suggests that the hypoxic fraction in a solid tumor may increase its malignant potential and reduce its sensitivity towards nonsurgical treatment modalities such as standard irradiation and certain anticancer agents1–5. However, the clinical importance of tumor hypoxia remains uncertain since valid methods for the routine measurement of intratumoral O2-tensions in patients have so far been lacking.

yearjournalcountryeditionlanguage
1994-01-01
https://doi.org/10.1007/978-1-4615-2468-7_59