6533b859fe1ef96bd12b81ee

RESEARCH PRODUCT

Studying Closed Hydrodynamic Models of "In Vivo" DNA Perfusion in Pig Liver for Gene Therapy Translation to Humans.

María José HerreroInmaculada NogueraMaria Adelaida Garcia-gimenoLuis SendraAntonio MiguelJudith Jazmin Castro PérezSalvador F. AliñoEva MontalváRafael López-andújarAna DíazLuis Martí-bonmatíDaniel Pérez-enguixPascual Sanz

subject

Male0301 basic medicineSwineCardiovascular ProceduresGenetic enhancementProtein ExpressionCellGene ExpressionMetal Nanoparticleslcsh:MedicineVascular SurgeryBiochemistryTranslational Research BiomedicalMice0302 clinical medicinePig ModelsGene expressionMedicine and Health SciencesTransgeneslcsh:ScienceMammalsMultidisciplinaryPhysicsGene Transfer TechniquesClassical MechanicsAgricultureAnimal ModelsPerfusionmedicine.anatomical_structureLivermedicine.veinOrgan SpecificityNaked DNA030220 oncology & carcinogenesisVertebratesPhysical SciencesFemalePerfusionPlasmidsResearch ArticleLivestockSurgical and Invasive Medical ProceduresFluid MechanicsBiologyGene deliveryResearch and Analysis MethodsContinuum MechanicsInferior vena cavaCatheterizationGene Delivery03 medical and health sciencesModel OrganismsIn vivoGene Expression and Vector TechniquesmedicineAnimalsHumansMolecular Biology TechniquesMolecular BiologyMolecular Biology Assays and Analysis TechniquesPlasma Proteinslcsh:ROrganismsBiology and Life SciencesProteinsFluid DynamicsDNAGenetic TherapyMolecular biology030104 developmental biologyalpha 1-AntitrypsinAmniotesHydrodynamicslcsh:QGold

description

17 páginas, 6 figuras. En la versión online contiene 3 figuras y 1 tabla en información suplemetaria

10.1371/journal.pone.0163898http://europepmc.org/articles/PMC5047531?pdf=render