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RESEARCH PRODUCT
One pot light assisted green synthesis, storage and antimicrobial activity of dextran stabilized silver nanoparticles.
Syed Nasir Abbas BukhariMuhammed Nawaz TahirAbdullah ShahMuhammad Ajaz HussainRiaz AhmedIbrahim JantanMuhammad Raza Shahsubject
inorganic chemicalsMaterials scienceSilverReducing agentScanning electron microscopeeducationBiomedical EngineeringDrug Evaluation PreclinicalMedicine (miscellaneous)Pharmaceutical ScienceMetal NanoparticlesNanotechnologyBioengineeringMicrobial Sensitivity TestsAntimicrobial activityMicroscopy Atomic ForceApplied Microbiology and BiotechnologySilver nanoparticleNanomaterialsStorage of nanoparticleschemistry.chemical_compoundAnti-Infective AgentsX-Ray DiffractionDiffused sun lightSpectroscopy Fourier Transform InfraredThin filmhealth care economics and organizationsAg nanoparticlesResearchtechnology industry and agricultureDextransGreen Chemistry TechnologySilver nitrateDextranchemistryMicroscopy Electron ScanningMolecular MedicineSilver NitrateSpectrophotometry UltravioletPowder diffractionNuclear chemistrydescription
Background Green synthesis of nanomaterials finds the edge over chemical methods due to its environmental compatibility. Herein, we report green synthesis of silver nanoparticles (Ag NPs) mediated with dextran. Dextran was used as a stabilizer and capping agent to synthesize Ag NPs using silver nitrate (AgNO3) under diffused sunlight conditions. Results UV–vis spectra of as synthesized Ag nanoparticles showed characteristic surface plasmon band in the range from ~405-452 nm. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) studies showed spherical Ag NPs in the size regime of ~50-70 nm. Face centered cubic lattice of Ag NPs was confirmed by powder X-ray diffraction (PXRD). FT-IR spectroscopy confirmed that dextran not only acts as reducing agent but also functionalizes the surfaces of Ag NPs to make very stable dispersions. Moreover, on drying, the solution of dextran stabilized Ag NPs resulted in the formation of thin films which were found stable over months with no change in the plasmon band of pristine Ag NPs. The antimicrobial assay of the as synthesized Ag NPs showed remarkable activity. Conclusion Being significantly active against microbes, the Ag NPs can be explored for antimicrobial medical devices.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-10-15 | Journal of nanobiotechnology |