6533b859fe1ef96bd12b8280

RESEARCH PRODUCT

Chromogenic and fluorogenic reagents for chemical warfare nerve agents' detection

Ramón Martínez-máñezAna M. CosteroSantiago RoyoSalvador GilFélix SancenónMargarita Parra

subject

Chemical WarfareSpecific detectionComputer scienceUNESCO::QUÍMICAOptical sensingNanotechnologyFluorogenic:QUÍMICA [UNESCO]CatalysisChromogenicOptical sensingMaterials ChemistrymedicineInstrumentation (computer programming)Nerve agentNerve agentsChromogenicUNESCO::QUÍMICA::Química analíticaToxixityMetals and AlloysGeneral ChemistrySurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsChromogenic ; Fluorogenic ; Chemical Warfare ; Nerve agents ; Toxixity ; Optical sensing:QUÍMICA::Química analítica [UNESCO]Ceramics and Compositesmedicine.drug

description

The ease of production, the extreme toxicity of organophosphorus-containing nerve agents, and their facile use in terrorism attacks underscores the need to develop accurate systems to detect these chemicals. Among different technologies we review here recent advances in the design of chromo-fluorogenic methods for the specific detection of nerve agents. Optical sensing (especially colorimetric detection) requires usually low-cost and widely used instrumentation and offers the possibility of so-called “naked eye detection”. Recent reported examples suggest that the application of chromo-fluorogenic supramolecular concepts for the chromogenic or fluorogenic sensing of nerve agents might be an area of increasing interest that would allow developing systems able to overcome some of the limitations shown by classical analytical methods. Costero Nieto, Ana Maria, Ana.Costero@uv.es ; Parra Alvarez, Margarita, Margarita.Parra@uv.es ; Gil Grau, Salvador, Salvador.Gil@uv.es

10.1039/b707063bhttp://hdl.handle.net/10550/16791