6533b859fe1ef96bd12b830f
RESEARCH PRODUCT
Mechanisms of resistance to autoimmune disease induced by T-cell vaccination.
Ansgar W. LohseIrun R. Cohensubject
Autoimmune diseaseEncephalomyelitis Autoimmune Experimentalbusiness.industrymedicine.medical_treatmentEncephalomyelitisT-LymphocytesImmunologyExperimental autoimmune encephalomyelitisT-cell vaccinationImmunization PassiveImmunotherapymedicine.diseaseImmune toleranceAutoimmune DiseasesVaccinationImmunoglobulin IdiotypesImmunopathologyImmunologymedicineImmune ToleranceImmunology and AllergyAnimalsbusinessdescription
Many human autoimmune diseases tend to progress slowly. Phases of rapid progression may come to a halt and may be followed by transient or even permanent remissions. Autoimmune diseases in animals either arise spontaneously or are induced. The former tend to be slowly progressive, the latter mostly acute to subacute, and usually followed by spontaneous remissions. The mechanisms at work that prevent rapid disease progression and can effect remissions are poorly understood, but they may provide us with a clue both to natural self-tolerance and to the therapeutic induction of self-tolerance.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1991-01-01 | Autoimmunity |