6533b85afe1ef96bd12b8b22

RESEARCH PRODUCT

ChemInform Abstract: Synthesis of Oligodeoxynucleotides Containing Diastereomeric Dihydrodiol Epoxide-N6-Deoxyadenosine Adducts of Polycyclic Aromatic Hydrocarbons.

Andreas BeckerAndreas BeckerJohn J. StezowskiJohn J. StezowskiThomas SteinbrecherFranz OeschAlbrecht Seidel

subject

Steric effectschemistry.chemical_compoundDeoxyadenosineStereochemistryChemistryDiastereomerNucleic acidEpoxideGeneral MedicineAdduct

description

Abstract A generally applicable route is reported for the synthesis of oligodeoxynucleotides which contain structurally defined N 6 -deoxyadenosine adducts, derived from sterically highly hindered dihydrodiol epoxides of polycyclic aromatic hydrocarbons (PAH).

https://doi.org/10.1002/chin.199330284