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RESEARCH PRODUCT

Fluorogenic Sensing of Carcinogenic Bisphenol A using Aptamer-Capped Mesoporous Silica Nanoparticles

Andrea BernardosPedro AmorósRamón Martínez-máñezM. Dolores MarcosÀNgela RibesFélix SancenónElena Aznar

subject

INGENIERIA DE LA CONSTRUCCIONendocrine systemBisphenol AAptamerMesoporous silica nanoparticlesAptamerNanoparticle02 engineering and technology010402 general chemistryElectron Microscopy Service of the UPV01 natural sciencesCatalysischemistry.chemical_compoundQUIMICA ORGANICAQUIMICA ANALITICARhodamine BOrganic chemistryreproductive and urinary physiologyCarcinogenDetection limiturogenital systemGated nanomaterialsQUIMICA INORGANICAOrganic ChemistryGeneral ChemistryMesoporous silica021001 nanoscience & nanotechnology0104 chemical sciencesBisphenol aFluorogenic sensingchemistry0210 nano-technologyhormones hormone substitutes and hormone antagonistsNuclear chemistry

description

[EN] Mesoporous silica nanoparticles loaded with rhodamine B and capped with a bisphenol A aptamer were used for the selective and sensitive detection of this lethal chemical. The pores of the nanoparticles are selectively opened in the presence of bisphenol A (through its selective coordination with the aptamer) with subsequent rhodamine B delivery. With this capped material a limit of detection as low as 3.5 mu m of bisphenol A was measured.

https://doi.org/10.1002/chem.201701024