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RESEARCH PRODUCT
The dynamics of the surface layer of lipid membranes doped by vanadium complex: computer modeling and EPR studies
Barbara PytelRyszard OlchawaDariusz Mansubject
Nuclear and High Energy PhysicsScienceDopingmembrane fluidityQAnalytical chemistryVanadiumchemistry.chemical_elementmonte carlo simulationCondensed Matter Physicslaw.inventionMembraneNuclear Energy and EngineeringchemistryChemical engineeringlawepr probeMembrane fluiditySurface layerlipid membraneSafety Risk Reliability and QualityElectron paramagnetic resonanceLipid bilayerWaste Management and DisposalInstrumentationdescription
Abstract Penetration of the liposome membranes doped with vanadium complex formed in the liquid-crystalline phase from egg yolk lecithin (EYL) by the TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) spin probes has been investigated. The penetration process was followed by 360 hours at 24°C, using the electron spin resonance (EPR) method. The spectroscopic parameter of the partition (F) of this probe indicated that a maximum rigidity of the membrane was at 3% concentration of the vanadium complex. Computer simulations showed that the increase in the rigidity of the membrane corresponds to the closure of gaps in the surface layer of the membrane, and indicates the essential role of the membrane surface in transport processes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-07-01 | Nukleonika |