Spotlight on fundus autofluorescence.

6533b85afe1ef96bd12b8e16

RESEARCH PRODUCT

Spotlight on fundus autofluorescence.

Ana M. Calvo-maroto Alejandro Cerviño

subject

medicine.medical_specialty genetic structures Review Lipofuscin chemistry.chemical_compound Ophthalmology Retinitis pigmentosa medicine lipofuscin Retinal pigment epithelium fundus autofluorescence business.industry near-infrared fundus autofluorescence short-wavelength fundus autofluorescence Retinal Diabetic retinopathy Macular degeneration medicine.disease Sensory Systems eye diseases melanin Ophthalmology medicine.anatomical_structure chemistry Choroid sense organs business Retinal Dystrophies

description

Fundus autofluorescence (FAF) imaging is based on the fluorescence from ocular endogenous fluorophores located in the retinal pigment epithelium and choroid, mainly lipofuscin and melanin. It is a noninvasive technique that provides information about the spatial distribution of lipofuscin/melanin and retinal pigment epithelium health status. An overview about the fluorophores responsible for FAF imaging and the usefulness of FAF imaging in the noninvasive assessment and monitoring of retinal diseases, such as age-related macular degeneration, diabetic retinopathy, diabetic macular edema, central serous chorioretinopthy, retinitis pigmentosa and retinal dystrophies, are discussed in this review.

year	journal	country	edition	language
2018-09-15	Clinical optometry

10.2147/opto.s134637 https://pubmed.ncbi.nlm.nih.gov/30214339

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