High-energy radiation process, a "facile" and "versatile" approach to obtain PVP-graft- AA nanogels

6533b85afe1ef96bd12b91bd

RESEARCH PRODUCT

High-energy radiation process, a "facile" and "versatile" approach to obtain PVP-graft- AA nanogels

Natascia Grimaldi Maria Antonietta Sabatino Giuseppe Spadaro Clelia Dispenza G Przybytniak I Kaluska

subject

Settore CHIM/07 - Fondamenti Chimici Delle Tecnologie Poly(N-vinylpyrrolidone) Acrylic acid grafting Nanogels E-beam irradiation.

description

Poly(N-vinylpyrrolidone)-grafted-acrylic acid biocompatible nanogels (NGs) were prepared using an exiting industrial-type electron accelerator and setups, starting from semi-dilute aqueous solutions of a commercial PVP and the acrylic acid monomer. As a result, NGs with tunable size and structure can be obtained quantitatively. Sterility was also imparted at the integrated dose absorbed. The chemical structure of the NGs produced was confirmed through Fourier Transformer Infrared Spectroscopy (FT-IR). The molecular and physico-chemical properties of NGs, such as the hydrodynamic dimensions and surface charge densities, for various polymer and monomer concentrations in the irradiated solutions, are discussed here.

year	journal	country	edition	language
2012-01-01

http://hdl.handle.net/10447/76833

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