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RESEARCH PRODUCT
Photoinduced functionalization of the C-20 methyl group of the nor-diterpene atractyligenin
Maurizio BrunoNicolò VivonaSilvestre BuscemiSergio RosselliFranco Piozzisubject
chemistry.chemical_compoundchemistryDecarboxylationOrganic ChemistryDrug DiscoverySurface modificationMethanolDiterpeneAtractyligeninBiochemistryMedicinal chemistryMethyl groupdescription
Abstract Irradiation of the nor-diterpene atractyligenin at λ =254 nm in methanol gave, on one hand, the decarboxylation product, and provided, on the other hand, the transformation of the C-20 angular methyl into a methylene-carbomethoxy group. A photochemical pathway involving formation of C-19/C-20 bond is suggested.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-11-01 | Tetrahedron Letters |