6533b85afe1ef96bd12b97f0

RESEARCH PRODUCT

MRSA ST22-IVa (EMRSA-15 clone) in Palermo, Italy

Bonura CelestinoPlano Maria Rosa AnnaPaola Di CarloCalà CinziaCipolla DomenicoCorsello GiovanniMammina CaterinaVella Antonietta

subject

clone (Java method)Methicillin-Resistant Staphylococcus aureusMeticillinEpidemiologyDrug resistanceMRSAMolecular typingmedicine.disease_causeHospitals GeneralMicrobiologylcsh:Infectious and parasitic diseasesDisease OutbreaksMolecular typingEpidemic spreadPrevalenceMedicineHumanslcsh:RC109-216EMRSA-15business.industrylcsh:Public aspects of medicinePublic Health Environmental and Occupational HealthOutbreaklcsh:RA1-1270General MedicineStaphylococcal Infectionsbiochemical phenomena metabolism and nutritionbacterial infections and mycosesVirologyInfectious DiseasesCross-Sectional StudiesItalyStaphylococcus aureusST22-IVAsense organsbusinessmedicine.drugBeta lactam antibiotics

description

Summary: Epidemic spread of methicillin-resistant Staphylococcus aureus (MRSA) strains carrying the Staphylococcal Chromosomal Cassettes (SCC) mec type IV is being increasingly reported in many geographical areas. A survey to determine the prevalence and characteristics of MRSA SCCmec IV isolates identified in four general hospitals in Palermo, Italy, was carried out. During the period February–June 2009, SCCmec type IVa has been found in 12 out of 94 isolates. Nine isolates from all hospitals and all strains from a NICU outbreak occurring in the same period were attributed with the ST22-IVa (EMRSA-15) clone. In our setting, due to the changing MRSA epidemiology, detection of SCCmec IV could be poorly predictive of CA-MRSA. Keywords: MRSA, ST22-IVA, EMRSA-15, Epidemiology, Molecular typing

10.1016/j.jiph.2010.09.004http://dx.doi.org/10.1016/j.jiph.2010.09.004